1493: Uncovering the New World Columbus Created
a larger image.
    Among these paradoxically cold-loving mosquitoes is Anopheles quadrimaculatus, the overall name for a complex of five near-indistinguishable sibling species. Like other Anopheles mosquitoes, A. quadrimaculatus hosts the parasite that causes malaria—the insect’s common name is the North American malaria mosquito. Southeast England at this time is rampant with malaria. Precise documentation will never become available, but there is good reason to suspect that by 1642 malaria has already traveled in immigrant bodies from England to the Americas. A single bite into an infected person is enough to introduce the parasite to its mosquito host, which spreads the parasite far and wide. Virginia and points south have already proven so unhealthy for Europeans that plantation overseers are finding it difficult to persuade laborers to come from overseas to work in the tobacco fields.
    Some landowners already have resolved this problem by purchasing workers from Africa. Partly driven by the introduction of malaria, a slave market is beginning to quicken into existence, a profitable exchange that will entwine itself over time with the silver market. As ever, the ships from Africa will form a kind of ecological corridor, through which travel passengers not on any official manifest. Crops like yams, millet, sorghum, watermelon, black-eyed peas, and African rice will follow the slave ships to the Americas. So will yellow fever.
    Beyond Chesapeake Bay the airplane flies west, heading toward Mexico. Beneath its wings unfurl the Great Plains. From their southern edge come herds of Spanish horses, scores at a time, brought by silver galleons on the return trip across the Atlantic. Apache and Ute race hundreds of miles south to meet the horses, followed by Arapaho, Blackfoot, and Cheyenne. As European villagers learned from Mongol horsemen, peasant farmers, tied to their land, are sitting ducks for cavalry assault. The rush by Indian nations to acquire horses is thus a kind of arms race. All over the North American West and Southwest, native farmers are abandoning their fields and leaping onto the backs of animals from Spain. Long-sedentary societies are becoming wanderers; the “ancient tradition” of the nomadic Plains Indian is coming into existence, a rapid adaptation to the Columbian Exchange.
    As natives acquire horses, they come into conflict with each other and the labor force on Spain’s expanding ranches. The ranch workers are Indians, African slaves, and people of mixed ancestry. In a kind of cultural panic, the colonial government has created a baroque racial lexicon—mestizo, mulatto, coyote, morisco, chino, lobo, zambaigo, albarazado —to label particular genetic backgrounds. All of these people and more meet in Mexico City, the capital of New Spain, the richest piece of Spain’s American empire. Wealthier and more populous than any city in Spain, it is an extraordinary jumble of cultures and languages, with no one group forming the majority. Neighborhoods are divided by ethnicity—one entire barrio is occupied by Tlaxcalans from the east. As the back-and-forth continues, engineers struggle to prevent the city from physical collapse. Mexico City has flooded six times in the last four decades, once remaining inundated for five years. A troubled, teeming, polyglot metropolis with an opulent center and seething ethnic neighborhoods at its periphery that is struggling to fend off ecological disaster—from today’s perspective, the Mexico City of 1642 seems strikingly familiar. It is the world’s first twenty-first-century city.
    The airplane flies west, to Acapulco, on Mexico’s Pacific coast, the eastern terminus of the galleon trade. Ringed by protective mountains, untroubled by sandbars or shoals, the harbor is a majestic setting for one of the more listless settlements in the Americas: several hundred huts scattered like lost clothes at the edge of the water. Most of Acapulco’s few permanent

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